Concurrent photothermal therapy and photodynamic therapy for cutaneous squamous cell carcinoma by gold nanoclusters under a single NIR laser irradiation

• DOI: 10.1039/c9tb01573f
• Publication Date: 2019-10-07T12:23:50Z
• Authors: Pei Liu; Weitao Yang; Lei Shi; Haiyan Zhang; Yan Xu; Peiru Wang; Guolong Zhang; Wei R. Chen; Bingbo Zhang; Xiuli Wang
• Keywords: CD4-Positive T-Lymphocytes; Drug Carriers; Mice, Hairless; Captopril; Skin Neoplasms; Singlet Oxygen; Cell Survival; Metal Nanoparticles; Antineoplastic Agents; Neoplasms, Experimental; 02 engineering and technology; CD8-Positive T-Lymphocytes; 3. Good health; Mice; Photochemotherapy; Cell Line, Tumor; Drug Design; Carcinoma, Squamous Cell; Animals; Female; Gold; Laser Therapy; 0210 nano-technology

The concurrent photothermal and photodynamic therapy of cutaneous squamous cell carcinoma by a single drug of Au25(Capt)18nanoclusters is demonstrated, together with a preliminary immune response study conducted under a single NIR laser irradiation.