A concise route to MK-4482 (EIDD-2801) from cytidine

• DOI: 10.1039/d0cc05944g
• Publication Date: 2020-10-02T14:03:33Z
• Authors: N. Vasudevan; Grace P. Ahlqvist; Catherine P. McGe...; Dinesh J. Paymode; Flavio S. P. Cardoso; Tobias Lucas; Jule-Phillip Dietz; Till Opatz; Timothy F. Jamison; Frank B. Gupton; David R. Snead
• Keywords: Cytidine

A two-step route to MK-4482 (EIDD-2801, 1) was developed consisting of an esterification and hydroxamination cytidine.