Manipulating the regioselectivity of a Solanum lycopersicum epoxide hydrolase for the enantioconvergent synthesis of enantiopure alkane- and alkene-1,2-diols

• DOI: 10.1039/d0cy00990c
• Publication Date: 2020-07-14T10:21:33Z
• Authors: Bochun Hu; Die Hu; Dong Zhang; Zheng Wen; Jia Zang; Minchen Wu
• Keywords: 01 natural sciences; 0104 chemical sciences

This work engineered a superior double-site mutant SlEH1W106T/F189L used for the enantioconvergent biosynthesis of (R)-1b–6b with high eep values.