Fucoxanthin alleviates palmitate-induced inflammation in RAW 264.7 cells through improving lipid metabolism and attenuating mitochondrial dysfunction

• DOI: 10.1039/d0fo00442a
• Publication Date: 2020-03-10T08:23:24Z
• Authors: Siyu Li; Xiaomeng Ren; Yuandong Wang; Jiangning Hu; Haitao Wu; Shuang Song; Chunhong Yan
• Keywords: Inflammation; Membrane Potential, Mitochondrial; 0301 basic medicine; Cell Survival; Inflammasomes; Interleukin-6; Tumor Necrosis Factor-alpha; Macrophages; Interleukin-1beta; Mitophagy; Palmitates; Gene Expression; Fatty Acids, Nonesterified; Xanthophylls; Lipid Metabolism; Mitochondria; 3. Good health; Mice; 03 medical and health sciences; RAW 264.7 Cells; NLR Family, Pyrin Domain-Containing 3 Protein; Animals

Fucoxanthin mitigated palmitate-induced inflammation in macrophages through promoting fatty acid oxidation and ameliorating mitochondrial dysfunction.