Ameliorative effects and molecular mechanisms of vine tea on western diet-induced NAFLD

• DOI: 10.1039/d0fo00795a
• Publication Date: 2020-06-24T11:10:57Z
• Authors: Kun Xie; Xi He; Keyu Chen; Kozue Sakao; De-Xing Hou
• Keywords: 0301 basic medicine; Kelch-Like ECH-Associated Protein 1; Ampelopsis; Carnitine O-Palmitoyltransferase; Flavonols; NF-E2-Related Factor 2; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Hep G2 Cells; AMP-Activated Protein Kinases; Diet, High-Fat; Lipid Metabolism; Antioxidants; Gastrointestinal Microbiome; 3. Good health; Mice, Inbred C57BL; 03 medical and health sciences; Liver; Diet, Western; Animals; Humans; Cytochrome P-450 CYP4A; Drugs, Chinese Herbal

VTP might prevent WD-induced NAFLD by balancing fatty acid oxidation and lipogenesis, hepatic oxidative stress, and the gut microbiome.