Mechanical phenotyping of breast cell lines by in-flow deformation-dependent dynamics under tuneable compressive forces

• DOI: 10.1039/d0lc00911c
• Publication Date: 2020-10-27T09:01:34Z
• Authors: David Dannhauser; Maria Isabella Ma...; Valeria Panzetta; Domenico Rossi; Paolo Antonio Netti; Filippo Causa
• Keywords: 0303 health sciences; MOTION; MIGRATION; ELLIPSOIDAL PARTICLES; Microfluidics; CAPSULE; SIMULATIONS; Cell Line; Motion; 03 medical and health sciences; LIQUID; SHEAR; ELLIPSOIDAL PARTICLES; SHEAR; DEFORMABILITY; MOTION; SIMULATIONS; MIGRATION; CAPSULE; LIQUID; Stress, Mechanical; Rheology; Cell Shape; DEFORMABILITY

Tuneable viscoelastic forces and a properly engineered microfluidic design induce in-flow deformation-dependent dynamics for cell mechanical measurements.