Selective extracellular arginine deprivation by a single injection of cellular non-uptake arginine deiminase nanocapsules for sustained tumor inhibition

• DOI: 10.1039/d0nr06823c
• Publication Date: 2020-11-17T07:43:53Z
• Authors: Hongzhao Qi; Yin Wang; Xubo Yuan; Peifeng Li; Lijun Yang
• Keywords: Argininosuccinate synthase; Arginine deiminase; Nanocapsules

Arginine deiminase nanocapsules possessing extremely weak cellular interaction could selectively deprive extracellular arginine to treat argininosuccinate synthetase-deficient tumors efficiently.