Regio- and diastereoselective synthesis of spiropyrroloquinoxaline grafted indole heterocyclic hybrids and evaluation of their anti-Mycobacterium tuberculosis activity

• DOI: 10.1039/d0ra02525a
• Publication Date: 2020-06-19T14:53:34Z
• Authors: Natarajan Arumugam; Abdulrahman I. Al...; Raju Suresh Kumar; Abdul Jaleel Moha...; Shatha Ibrahim Al...; Sevgi Kansız; Vagolu Siva Krishna; Dharmarajan Sriram; Necmi Dege
• Keywords: Chemistry; 01 natural sciences; 0104 chemical sciences; 3. Good health

An efficient and eco compatible approach for the regio- and stereoselective synthesis of structurally diverse novel spiropyrrolidine tethered indole hybrids in excellent yields employing a one-pot multicomponent 1,3-dipolar cycloaddition strategy.