Exploring the inner environment of protein hydrogels with fluorescence spectroscopy towards understanding their drug delivery capabilities

• DOI: 10.1039/d0tb00818d
• Publication Date: 2020-06-01T13:43:50Z
• Authors: Ramesh Nandi; Anna Yucknovsky; Manuel M. Mazo; Nadav Amdursky
• Keywords: Drug Carriers; Hydrogels; Serum Albumin, Bovine; Hydrogen-Ion Concentration; 01 natural sciences; 3. Good health; 0104 chemical sciences; Drug Liberation; Spectrometry, Fluorescence; Doxorubicin; Cell Line, Tumor; Humans; Hydrophobic and Hydrophilic Interactions

Time-resolved fluorescence have used to explore the inner surface and solvation dynamics within protein hydrogels assisting in rationalizing their drug binding release capabilities.