In situreal time monitoring of emulsification and homogenization processes for vaccine adjuvants

• DOI: 10.1039/d1an01797g
• Publication Date: 2021-12-15T11:35:00Z
• Authors: Nicole M. Ralbovsky; Randal J. Soukup; Justin P. Lomont; Mackenzie L. Lauro; Amanda Gulasarian; Anumita Saha-Shah; Michael A. Winters; Douglas D. Richar...; Sheng-Ching Wang; Ian Mangion; Joseph P. Smith
• Keywords: Humans; Emulsions; Particle Size; Adjuvants, Vaccine; Spectrum Analysis, Raman; 01 natural sciences; 0104 chemical sciences; 3. Good health

Process analytical technology was used to monitor formation of a stable emulsion product, with results providing improved understanding of emulsion-based vaccine adjuvant formation processes.