A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles

• DOI: 10.1039/d1cb00200g
• Publication Date: 2021-12-08T03:22:11Z
• Authors: Darielys Santana-...; Rocmira Perez-Nicado; Yanet Climent; Laura Rodriguez; Belinda Sanchez R...; Sonia Perez-Rodri...; Meybi Rodriguez; Claudia Labrada; Tays Hernandez; Marianniz Diaz; Ivette Orosa; Ubel Ramirez; Reynaldo Oliva; Raine Garrido; Felix Cardoso; Mario Landys; Roselyn Martinez; Humberto Gonzalez; Tamara Hernandez; Rolando Ochoa-Azze; Jose L. Perez; Juliet Enriquez; Nibaldo Gonzalez; Yenicet Infante; Luis A. Espinosa; Yassel Ramos; Luis Javier González; Carmen Valenzuela; Ana Victoria Casa...; Briandy Fernandez; Gertrudis Rojas; Beatriz Pérez-Massón; Yaima Tundidor; Ernesto Bermudez; Claudia A. Plasencia; Tammy Boggiano; Eduardo Ojito; Fabrizio Chiodo; Sonsire Fernandez; Françoise Paquet; Cheng Fang; Guang-Wu Chen; Daniel G. Rivera; Yury Valdes-Balbin; Dagmar Garcia-Rivera; Vicente Verez Ben...
• Keywords: [SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases; 0301 basic medicine; Chemistry; 03 medical and health sciences; [SDV.IMM.VAC] Life Sciences [q-bio]/Immunology/Vaccinology; [SDV]Life Sciences [q-bio]; [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases; 3. Good health

Soberana01 is composed of the SARS-CoV-2 dimeric RBD and Neisseria meningitidis outer membrane vesicles (OMVs) adsorbed on alum. This vaccine induces a potent neutralizing immune response and shows potential against SARS-CoV-2 variants of concern.