Radiosynthesis and evaluation of a fluorine-18 radiotracer [18F]FS1P1 for imaging sphingosine-1-phosphate receptor 1

• DOI: 10.1039/d1ob02225c
• Publication Date: 2021-12-31T18:21:23Z
• Authors: Lin Qiu; Hao Jiang; Yanbo Yu; Jiwei Gu; Jinzhi Wang; Haiyang Zhao; Tianyu Huang; Robert J. Gropler; Robyn S. Klein; Joel S. Perlmutter; Zhude Tu
• Keywords: Radiosynthesis; Fluorine; Sphingosine-1-phosphate receptor; PET Imaging

A promising sphingosine-1-phosphate receptor 1 PET radiotracer [ 18 F]FS1P1 was synthesized using a facile multiple step F-18 radiochemistry procedure.