β-Blockers bearing hydroxyethylamine and hydroxyethylene as potential SARS-CoV-2 Mpro inhibitors: rational based design,in silico,in vitro, and SAR studies for lead optimization

• DOI: 10.1039/d1ra04820a
• Publication Date: 2021-11-03T16:14:04Z
• Authors: Mohammed I. A. Hamed; Khaled M. Darwish; Raya Soltane; Amani Chrouda; Ahmed Mostafa; Noura M. Abo Shama; Sameh S. Elhady; Hamada S. Abulkhair; Ahmed E. Khodir; Ayman Abo Elmaaty; Ahmed A. Al-karma...
• Keywords: 0301 basic medicine; Chemistry; 0303 health sciences; 03 medical and health sciences; 01 natural sciences; 0104 chemical sciences; 3. Good health

Hydroxyethylamine and hydroxyethylene moieties of β-blockers exert potential SARS-CoV-2 inhibitory effects: rational-based design andin silico,in vitro, and SAR Studies.