Ultra-thin metal–organic framework nanosheets for chemo-photodynamic synergistic therapy

• DOI: 10.1039/d1tb00528f
• Publication Date: 2021-04-26T11:01:24Z
• Authors: Rui Zeng; Tingting He; Lu Lu; Ke Li; Zhong Luo; Kaiyong Cai
• Keywords: Mice, Inbred BALB C; Antibiotics, Antineoplastic; Cell Survival; Mammary Neoplasms, Experimental; Mice, Nude; Apoptosis; 02 engineering and technology; 3. Good health; Mice; Drug Delivery Systems; Photochemotherapy; Doxorubicin; Tumor Cells, Cultured; Animals; Nanoparticles; Female; Drug Screening Assays, Antitumor; 0210 nano-technology; Metal-Organic Frameworks; Cell Proliferation

A bottom-up strategy was developed to fabricate ultra-thin DOX@Cu–TCPP nanosheets, demonstrating effective chemo-photodynamic synergistic therapy against triple-negative breast cancer.