Merging C–C σ-bond activation of cyclobutanones with CO2 fixation via Ni-catalysis

• DOI: 10.1039/d2cc00149g
• Publication Date: 2022-02-25T13:00:57Z
• Authors: Lorenzo Lombardi; Alessandro Cerveri; Leonardo Ceccon; Riccardo Pedrazzani; Magda Monari; Giulio Bertuzzi; Marco Bandini
• Keywords: Carbon Dioxide; 01 natural sciences; CO2, Nickel catalysis, C-C bond activation, carboxylation, cyclobutanone; Catalysis; 0104 chemical sciences

A carboxylative Ni-catalyzed tandem C–C σ-bond activation of cyclobutanones followed by CO2-electrophilic trapping is documented as a direct route to synthetically valuable 3-indanone-1-acetic acids.