Highly sensitive acetylcholine biosensing via chemical amplification of enzymatic processes in nanochannels

• DOI: 10.1039/d2cc02249d
• Publication Date: 2022-08-11T12:01:25Z
• Authors: Yamili Toum Terrones; Gregorio Laucirica; Vanina M. Cayón; Gonzalo E. Fenoy; M. Lorena Cortez; María Eugenia Toi...; Christina Trautmann; Waldemar A. Mamis...; Omar Azzaroni
• Keywords: Ions; nanofluidic sensing; nanochannels; Polyelectrolytes; 01 natural sciences; Acetylcholine; 0104 chemical sciences; acetylcholine biosensing; https://purl.org/becyt/ford/1.4; Acetylcholinesterase; biosensing; https://purl.org/becyt/ford/1

In this work, we present the ultra-sensitive detection of acetylcholine (Ach) using enzymatic nanofluidic biosensors in which the ionic signal is generated via local chemical amplification of enzymatic processes.