Iron-catalyzed deconstructive alkylation through chlorine radical induced C–C single bond cleavage under visible light

• DOI: 10.1039/d2cc03896j
• Publication Date: 2022-08-12T13:22:43Z
• Authors: Qiang Wu; Wei Liu; Miao Wang; Yahao Huang; Peng Hu
• Keywords: Cleavage (geology); Bond cleavage; Visible spectrum

Selective C-C single bond cleavage of simple compounds is a highly challenging and desired process. Herein, chlorine radical-induced deconstructive alkylation with alcohols alkenes catalyzed by iron salts was reported for the first time. Readily available various electron-deficient were tolerated. Late-stage large-scale reactions proceed smoothly. This catalyst system shows potential diversified functionalization bonds.