Ferrocene-appended anthraquinone and coumarin as redox-active cytotoxins

• DOI: 10.1039/d2dt01251k
• Publication Date: 2022-07-05T21:01:06Z
• Authors: Aryan Houshmand; Devon Heroux; Dennis Y. Liu; Wen Zhou; Roger G. Linington; Marcel Bally; Jeffrey J. Warren; Charles J. Walsby
• Keywords: Coumarins; Cytotoxins; Metallocenes; Humans; Anthraquinones; Hydrogen Peroxide; Reactive Oxygen Species; Oxidation-Reduction; 01 natural sciences; 0104 chemical sciences; 3. Good health

Appending ferrocene to coumarin and anthraquinone promotes generation of hydroxyl radicals and modulates anticancer activity.