Inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by hydroxylated xanthones

• DOI: 10.1039/d2fo00023g
• Publication Date: 2022-06-15T07:40:51Z
• Authors: Clementina M. M. ...; Carina Proença; Marisa Freitas; Alberto N. Araújo; Artur M. S. Silva; Eduarda Fernandes
• Keywords: 0301 basic medicine; Mangostin; Xanthones; Diabetes; Carbohydrates; Amylase; alpha-Glucosidases; Xanthone; 03 medical and health sciences; Diabetes Mellitus, Type 2; Mangiferin; Humans; Hypoglycemic Agents; Glycoside Hydrolase Inhibitors; Glucosidase; alpha-Amylases; Inhibition; SAR

A group of hydroxylated xanthones as promising inhibitors of key enzymes are involved in glucose metabolism and therefore in the management of type 2 diabetes mellitus.