Nucleic acid-based supramolecular structures: vesicular spherical nucleic acids from a non-phospholipid nucleolipid

• DOI: 10.1039/d2na00527a
• Publication Date: 2022-08-09T07:21:23Z
• Authors: Erik Dimitrov; Natalia Toncheva-...; Pavel Bakardzhiev; Aleksander Forys; Jordan Doumanov; Kirilka Mladenova; Svetla Petrova; Barbara Trzebicka; Stanislav Rangelov
• Keywords: Nucleic acid structure; Residue (chemistry)

An original hybrid biomacromolecule, consisting of a lipid-mimetic residue and 21-base long nucleic acid strand, spontaneously self-associates co-associates with other lipids into acid-grafted vesicular structures.