Atropisomeric 9,10-dihydrophenanthrene/bibenzyl trimers with anti-inflammatory and PTP1B inhibitory activities from Bletilla striata

• DOI: 10.1039/d2ob00489e
• Publication Date: 2022-05-25T00:21:03Z
• Authors: Mohan Sun; Xianjie Ma; Siyuan Shao; Jianwei Jiang; Jiaan Li; Jinying Tian; Jianjun Zhang; Li Li; Fei Ye; Shuai Li
• Keywords: Plant Tubers; 0303 health sciences; 03 medical and health sciences; Polymers; Bibenzyls; Anti-Inflammatory Agents; Orchidaceae; 3. Good health

Two pairs of novel trimeric dihydrophenanthrene–bibenzyl–dihydrophenanthrene enantiomers, together with three rare polymers were isolated from Bletilla striata. Some compounds showed significant anti-inflammatory and PTP1B inhibitory activities.