Copper-promoted cross-coupling of nitroarenes with 4-alkyl-1,4-dihydropyridines using a peroxide-driven radical reductive strategy

• DOI: 10.1039/d2qo00706a
• Publication Date: 2022-06-17T07:41:20Z
• Authors: Hui-Min Jiang; Jing-Hao Qin; Qing Sun; Dong Zhang; Jin-Peng Jiang; Xuan-Hui Ouyang; Ren-Jie Song; Jin-Heng Li
• Keywords: Peroxide; Coupling reaction

Direct radical-mediated reductive coupling of nitroarenes with 4-alkyl-1,4-dihydropyridines to build the C(sp 3 )–N bond using as internal reducing agents and alkyl sources is presented.