A double-network strategy for the tough tissue adhesion of hydrogels with long-term stability under physiological environment

• DOI: 10.1039/d2sm00688j
• Publication Date: 2022-07-01T06:21:15Z
• Authors: Shuyang Wang; Jieru Li; Yudong Pan; Fengkai Liu; Liangsong Zeng; Yang Gao; Tongqing Lu
• Keywords: Alginates; Swine; Animals; Hydrogels; Tissue Adhesions; 02 engineering and technology; 0210 nano-technology; Hydrophobic and Hydrophilic Interactions; 01 natural sciences; Mechanical Phenomena; 0104 chemical sciences

We propose a facile “double-network” strategy for tough hydrogel adhesive with long-term stability under the physiological environment. The primary network is covalently crosslinked with tunable hydrophilicity, and the secondary network is noncovalently crosslinked.