A comprehensive and high-throughput screening method for multiple prohibited substances by UPLC-QE Plus-HRMS and HPLC-QQQ-MS in human urine for doping control

• DOI: 10.1039/d3ay00424d
• Publication Date: 2023-06-07T08:41:17Z
• Authors: Yunxi Liu; Tianyu Dong; Kuan Yan; Zhanliang Wang; Genye He; Yufeng Zhang; Congcong Ma; Lu Liu; Wei Chang; Lisi Zhang
• Keywords: Anabolic Agents; Humans; Diuretics; Glucocorticoids; Chromatography, High Pressure Liquid; Mass Spectrometry; 3. Good health; High-Throughput Screening Assays

A newly combined, comprehensive, rapid and high-throughput doping control screening method for the analysis of 350 substances with different polarities in human urine using UPLC-QE Plus-HRMS and UPLC-QQQ-MS has been developed and validated.