Implementation of micelle-enabled C(sp2)–C(sp3) cross-electrophile coupling in pharmaceutical synthesis
Aqueous medium
Dual role
Electrophilic substitution
DOI:
10.1039/d3cc05916b
Publication Date:
2024-01-22T07:05:14Z
AUTHORS (15)
ABSTRACT
A sustainable C(sp 2 )–C(sp 3 ) cross-electrophile coupling was developed between readily available 5-bromophthalide and 1-benzyl-4-iodopiperidine under micellar conditions, leading to a key intermediate of one our development compounds.
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CITATIONS (8)
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