Secondary-structure phase formation for semiflexible polymers by bifurcation in hyperphase space

• DOI: 10.1039/d3cp02815a
• Publication Date: 2023-10-18T15:02:39Z
• Authors: Dilimulati Aierken; Michael Bachmann
• Keywords: Inflection point; Structural Stability; Hyperspace

Canonical analysis has long been the primary method for studies of phase transitions. However, this approach is not sensitive enough if transition signals are too close in temperature space. The recently introduced generalized microcanonical inflection-point only enables systematic identification and classification transitions systems any size, but it can also distinguish that standard canonical cannot resolve. By applying to a generic coarse-grained model semiflexible polymers, we identify mixed structural dominated by secondary structures such as hairpins loops originates from bifurcation hyperspace spanned inverse bending stiffness. This intermediate phase, which embraced well-known random-coil toroidal phases, testimony necessity balancing entropic variability energetic stability functional macromolecules under physiological conditions.