Integrated multi-omics profiling highlights the benefits of resveratrol hydroxypropyl-β-cyclodextrin inclusion complex for A53T transgenic mice through the microbiota–gut–brain axis

• DOI: 10.1039/d3fo03667g
• Publication Date: 2024-01-10T01:42:37Z
• Authors: Xiaodong Sun; Shenglan Feng; Bingqing Qin; Junjie Ye; Lixia Xie; Jianjun Gui; Ming Sang
• Keywords: 0301 basic medicine; Mice; 03 medical and health sciences; Resveratrol; Brain-Gut Axis; Humans; Animals; Mice, Transgenic; Parkinson Disease; Multiomics; 2-Hydroxypropyl-beta-cyclodextrin

Parkinson's disease is a neurological disorder characterized by motor and gastrointestinal dysfunctions. Resveratrol HP-B-CD inclusion complex improved motor dysfunction and pathological progression of A53T mice through the microbiota-gut-brain axis.