A CDAHFD-induced mouse model mimicking human NASH in the metabolism of hepatic phosphatidylcholines and acyl carnitines

• DOI: 10.1039/d3fo05111k
• Publication Date: 2024-02-27T12:59:51Z
• Authors: Jie Yang; Manyun Dai; Ying Wang; Zheng Yan; Shuqi Mao; Aiming Liu; Caide Lu
• Keywords: 0303 health sciences; 03 medical and health sciences

Lipidomics reavealed the differences of lipid signitures in NASH models induced by MCD and CDAHFD mice. The hepatic PCs, ACs their metabolism CDAHFD-treated mice were down-regulated, mimicking human NASH.