Femtosecond laser modified metal surfaces alter biofilm architecture and reduce bacterial biofilm formation

• DOI: 10.1039/d3na00599b
• Publication Date: 2023-10-17T15:13:46Z
• Authors: Iaroslav Gnilitskyi; Svitlana Rymar; Olga Iungin; Olexiy Vyshnevskyy; Pietro Parisse; Geert Potters; Anatoly V. Zayats; Olena Moshynets
• Keywords: Biofouling

Biofilm formation, or microfouling, is a basic strategy of bacteria to colonise surface and may happen on surfaces any nature whenever are present. Biofilms hard eradicate due the matrix in which reside, consisting strong, adhesive adaptive self-produced polymers such as eDNA functional amyloids. Targeting biofilm be promising prevent formation. Here, femtosecond laser irradiation was used modify stainless steel order introduce either conical spike groove textures. The resulting topography consists hierarchical nano-microstructures substantially increase roughness. biofilms two model bacterial strains, P. aeruginosa PA01 S. aureus ATCC29423, formed nanotextured metal surfaces, were considerably modified substantial reduction amyloid production changes adhesion, leading significant biomass. Altering surface, therefore, radically diminishes development solely by altering architecture. At same time, growth colonisation eukaryotic adipose tissue-derived stem cells apparently enhanced, possible further advantages controlling while suppressing prokaryotic contamination. obtained results important for developing anti-bacterial numerous applications.