Palladium-catalyzed domino cyclization/direct functionalization involving the insertion of SO2

• DOI: 10.1039/d3nj05872g
• Publication Date: 2024-02-26T13:20:43Z
• Authors: Xinwei Zhang; Yaoyao Lu; Shuoshuo Zhang; Shuizhen Lin; Mengting Chen; Xiaolei Huang

A reductive cross-coupling strategy for the synthesis of sulfone-containing oxindoles was presented. Moreover, using amines instead of alkyl bromides, a palladium-catalyzed domino cyclization/aminosulfonylation was also established.