An aerobic copper-catalyzed multi-component reaction strategy for N′,N′-diaryl acylhydrazine synthesis: reactions and mechanism

• DOI: 10.1039/d3qo01768k
• Publication Date: 2023-12-20T00:43:50Z
• Authors: Lei Deng; Wei Guo; Xiaojuan Yang; Lvyin Zheng; Yingying Wu; Beining Yang; Yihan Wang; Deliang Chen
• Keywords: 01 natural sciences; 0104 chemical sciences

A sequential multi-component reaction of aldehydes and aryl hydrazines for the synthesis of N',N'-diaryl acylhydrazines with high regioselectivity has been achieved via an aerobic copper-catalyzed process.