Synthesis of triazole bridged N-glycosides of pyrazolo[1,5-a]pyrimidinones as anticancer agents and their in silico docking studies

• DOI: 10.1039/d3ra06993a
• Publication Date: 2024-01-03T11:22:51Z
• Authors: Ghanshyam Tiwari; Vinay Kumar Mishra; Priti Kumari; Ashish Khanna; Sunil Sharma; Ram Sagar
• Keywords: Chemistry; 01 natural sciences; 0104 chemical sciences

An efficient microwave assisted synthesis of diverse triazole bridged N-glycosides of pyrazolo[1,5-a]pyrimidinones as new glycohybrids has been developed. The anti-cancer property of these glycohybrids was evaluated against MCF-7, MDA-MB231 and MDA-MB453 cell lines.