GSH-activatable camptothecin prodrug-loaded gold nanostars coated with hyaluronic acid for targeted breast cancer therapy via multiple radiosensitization strategies

• DOI: 10.1039/d3tb00965c
• Publication Date: 2023-09-05T07:41:21Z
• Authors: Yingke Hou; Bin Sun; Rongtian Li; Wei Meng; Wenhua Zhang; Nuan Jia; Ming Chen; Jinxiang Chen; Xiaoyan Tang
• Keywords: Tumor Microenvironment; Humans; Female; Prodrugs; Breast Neoplasms; Camptothecin; Gold; Disulfides; Hyaluronic Acid; Hypoxia; Glutathione

The nanoplatform of ASH was constructed for synergetic chemotherapy/photothermal/radiation therapy to stimulate the immunogenic cell death process for breast cancer treatment.