Pretargeted radiotherapy and synergistic treatment of metastatic, castration-resistant prostate cancer using cross-linked, PSMA-targeted lipoic acid nanoparticles

• DOI: 10.1039/d3tb02543h
• Publication Date: 2024-02-01T15:21:06Z
• Authors: Liqun Dai; Xiaoyang Zhang; Siming Zhou; Jie Li; Lili Pan; Chunyan Liao; Zhipeng Wang; Ying Chen; Guohua Shen; Lin Li; Rong Tian; Hongbao Sun; Zhenhua Liu; Shiyong Zhang; Haoxing Wu
• Keywords: 0301 basic medicine; 03 medical and health sciences

A potent strategy based on cross-linked, PSMA-targeted lipoic acid nanoparticles revealed the great potential of pretargeted radiotherapy for the synergistic treatment of metastatic castration-resistant prostate cancer.