Investigating serum concentration profiles of orally ingested short-chain fatty acid supplements

• DOI: 10.1039/d4fo04028g
• Publication Date: 2024-10-30T08:41:16Z
• Authors: Christopher G. Green; Marilyn L. Y. Ong; Samantha N. Rowland; Tindaro Bongiovanni; Lewis J. James; Tom Clifford; Stephen J. Bailey; Liam M. Heaney
• Keywords: dietary supplements; Male; Adult; Fatty Acids, Volatile/blood; Humans; young adult; Administration, Oral; Female; Propionates/blood; Middle Aged; Butyrates/blood

HPMC capsules containing acetate, propionate, and butyrate salts exhibit peak serum concentrations of each short-chain fatty acid within 60 min and a return to baseline within 120 min. Seven days of repeated intake does not alter basal serum levels.