Differential Mg2+ deposition on DNA Holliday Junctions dictates the rate and stability of conformational exchange

• DOI: 10.1039/d4nr02411g
• Publication Date: 2024-11-05T16:00:54Z
• Authors: Pratibha Agarwala; Arumay Pal; Milan Kumar Hazra; Dibyendu K. Sasmal

DNA Holliday junctions (HJs) are crucial intermediates in genetic recombination and genome repair processes, characterized by a dynamic nature and transitioning among multiple conformations on the timescale ranging from sub-milliseconds to seconds.