Biosynthesis of the bacterial antibiotic 3,7-dihydroxytropolone through enzymatic salvaging of catabolic shunt products

Catabolism
DOI: 10.1039/d4sc01715c Publication Date: 2024-04-24T07:41:06Z
ABSTRACT
The biosynthesis of the bacterial antibiotic dihydroxytropolone was reconstituted in vitro starting from a catabolic shunt product. involved key flavoprotein monooxygenase TrlE further structurally and mechanistically characterized.
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