Neurogenic and angiogenic poly(N-acryloylglycine)-co-(acrylamide)-co-(N-acryloyl-glutamate) hydrogel: preconditioning effect under oxidative stress and use in neuroregeneration

• DOI: 10.1039/d4tb00243a
• Publication Date: 2024-05-24T16:16:31Z
• Authors: Kirti Wasnik; Prem Shankar Gupta; Gurmeet Singh; Somedutta Maity; Sukanya Patra; Divya Pareek; Sandeep Kumar; Vipin Rai; Ravi Prakash; Arbind Acharya; Pralay Maiti; Sudip Mukherjee; Yitzhak Mastai; Pradip Paik
• Keywords: 0301 basic medicine; 0303 health sciences; Polymers; Neurogenesis; Neovascularization, Physiologic; Hydrogels; Biocompatible Materials; Antineoplastic Agents; PC12 Cells; Rats; Oxidative Stress; Human Umbilical Vein Endothelial Cells; Humans; Animals; Cell Proliferation

[p(NAG-Ac-NAE)] mimic cellular microenviroment by facilitating neuronal stem cell migration towards the injured site via aniogenesis and induce recovery.