Synthesis of the Tricyclic Skeleton of Aberrarone

• DOI: 10.1039/d5ob00644a
• Publication Date: 2025-05-21T11:21:04Z
• Authors: Guoqing Sui; Xiaoqing Song; Huihui Guo; Xiaolan Xie; Li Ren; Wenming Zhou; Hongdong Hao

A synthesis of the 6-5-5 tricyclic skeleton of the diterpenoid aberrarone is reported. The synthesis strategically features an intermolecular Diels-Alder reaction to construct the cis-hydrindane moiety and a cross coupling-isomerization-intramolecular...