Incorporation of [18O]water in the formation of p-hydroxybenzyl alcohol by the p-cresol methylhydroxylase from Pseudomonas putida

0301 basic medicine Chemistry Cresols 0303 health sciences 03 medical and health sciences Chemical Phenomena Pseudomonas Benzyl Compounds Water Benzyl Alcohols Mixed Function Oxygenases 3. Good health
DOI: 10.1042/bj1750345 Publication Date: 2015-08-10T20:13:23Z
ABSTRACT
In the hydroxylation of the methyl group of p-cresol by an enzyme from Pseudomonas putida the oxygen atom is derived from water. Although a second reaction by the same enzyme converts the product, p-hydroxybenzyl alcohol, into the aldehyde, the alcohol is an enzyme-free intermediate.
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