Incorporation of [18O]water in the formation of p-hydroxybenzyl alcohol by the p-cresol methylhydroxylase from Pseudomonas putida
0301 basic medicine
Chemistry
Cresols
0303 health sciences
03 medical and health sciences
Chemical Phenomena
Pseudomonas
Benzyl Compounds
Water
Benzyl Alcohols
Mixed Function Oxygenases
3. Good health
DOI:
10.1042/bj1750345
Publication Date:
2015-08-10T20:13:23Z
AUTHORS (1)
ABSTRACT
In the hydroxylation of the methyl group of p-cresol by an enzyme from Pseudomonas putida the oxygen atom is derived from water. Although a second reaction by the same enzyme converts the product, p-hydroxybenzyl alcohol, into the aldehyde, the alcohol is an enzyme-free intermediate.
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