Increased Intralymphocytic Sodium Content in Essential Hypertension: An Index of Impaired Na+ Cellular Metabolism

• DOI: 10.1042/cs0610181
• Publication Date: 2015-08-07T10:38:55Z
• Authors: E. Ambrosioni; F. V. Costa; L. Montebugnoli; F. Tartagni; B. Magnani
• Keywords: Essential hypertension

1. The sodium concentration in lymphocytes was measured a group of 66 normotensive subjects (40 without familial hypertension and 26 with hypertension), 81 patients essential 14 secondary hypertension. 2. mean value (+/- SD) no history 21.9 +/- 3.1 mmol/kg wet weight, which significantly lower (P less than 0.005) that (mean 27.9 4.2 mmol/kg). Lymphocyte higher (33.2 3.3 mmol/kg; P 0.001) the normal blood pressure 3. In there significant correlation between lymphocyte systolic 0.005), diastolic pressure. 4. forms had concentration, except case Conn's disease. 5. Incubation ouabain increased hypertension; final similar two groups. 6. When from were incubated plasma an increase their content.