Effects of dietary organic chromium on gilthead seabream (Sparus aurata L.) performances and liver microsomal metabolism

• DOI: 10.1046/j.1355-557x.2001.00005.x
• Publication Date: 2003-03-11T04:13:47Z
• Authors: P P Gatta; A Piva; M Paolini; S Testi; A Bonaldo; A Antelli; A Mordenti
• Keywords: 0303 health sciences; 03 medical and health sciences; Chromium; Gilthead seabream; Nutrition; Toxicology

The effect of yeast and chromium on gilthead seabream (Sparus auratus L) performance, carcass indices body composition was studied. Whether supplementation affected liver microsomal mixed function oxidases using either multibioprobes (testosterone) or highly specific substrates to cytochrome P450 (CYP) isoforms also investigated. Seabream juveniles (35–37 g initial weight) were allocated into 12 800 L tanks 50 fish each for 87 days fed pelleted experimental diets, i.e. control, supplemented (1.6%) at both low (800 p.p.b.) high level (53 810 p.p.b.). At the end experiment, growth, feed conversion ratio, thermal-unit growth coefficient, yield, hepatosomatic index, fillet proximate compositions similar among treatments only condition factor statistically different. Organic doses CYP-catalysed drug reactions slightly, as shown by modest regio- stereoselective hydroxylations testosterone, well metabolism selected probes. Overall, we found that did not change performance substantially, nor indices, chemical compositions, hepatic xenobiotic metabolizing enzymes seabream.