Crete: does farming explain urban and rural differences in atopy?

• DOI: 10.1046/j.1365-2222.2001.01240.x
• Publication Date: 2003-03-11T09:46:07Z
• Authors: M. Barnes; P. Cullinan; P. Athanasaki; S. MacNeill; A. M. Hole; J. Harris; S. Kalogeraki; M. Chatzinikolaou; N. Drakonakis; V. Bibaki‐Liakou; A. J. Newman Taylor; I. Bibakis
• Keywords: Atopy; Capital city; Cross-sectional study

Background Urban‐rural differences in the prevalence of atopy and associated allergic diseases have been reported several non‐European countries. Within Europe, where such variations are less striking, a farm childhood has postulated to be protective. Objective We aimed compare urban rural children living Crete examine role early exposure farming environment explaining any measured differences. Methods A cross‐sectional survey attending secondary schools Iraklion, capital city, five villages 100 km south. Atopy was determined by responses skin prick tests with seven common aeroallergens. Results Nine‐nundred ninety‐seven participated survey. 19.6% those but only 9.6% from villages, had positive response one or more tests. Among there were significant gradients across categories animal contact consumption (unpasteurized) milk products – before age 5 years. These differences, however, not apparent among children.