Wet- versus dry-suction techniques for endoscopic ultrasound-guided fine-needle aspiration of solid lesions: a multicenter randomized controlled trial

• DOI: 10.1055/a-1167-2214
• Publication Date: 2020-05-15T22:53:08Z
• Authors: Yun Wang; Rong-hua Wang; Zhen Ding; Shi-yun Tan; Qian Chen; Ya-qi Duan; Liang-ru Zhu; Ji-wang Cao; Jian Wang; Gan Shi; Xiao-li Wu; Jin-lin Wang; Yu-chong Zhao; Shou-jiang Tang; Bin Cheng
• Keywords: Endoscopic Ultrasound

Abstract Background The optimal sampling techniques for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) remain unclear and have not been standardized. aim of this study was to compare the wet-suction dry-suction solid lesions in pancreas, mediastinum, abdomen. Methods This a multicenter, crossover, randomized controlled trial with order techniques. 296 consecutive patients underwent EUS-FNA 22G needles were ratio 1:1 into two separate groups that received different order. primary outcome histological diagnostic accuracy dry suction wet malignancy. secondary outcomes cytological specimen quality. Results Among 269 pancreatic (n = 161) non-pancreatic 108) analyzed, technique had significantly better (84.9 % [95 confidence interval (CI) 79.9 – 89.0 %] vs. 73.2 %CI 67.1 78.7 %]; P 0.001), higher adequacy (94.8 78.8 %; < less blood contamination (P 0.001) than technique. In addition, passes provided 91.6 %. Conclusions generates quality Furthermore, may provide definitive diagnosis when rapid on-site evaluation is routinely available.