Preliminary assessment of the chemical stability of dried extract from Guazuma ulmifolia Lam. (Sterculiaceae)

• DOI: 10.1055/s-0029-1234713
• Publication Date: 2009-09-24T04:59:32Z
• Authors: GC Lopes; R Longuini; T Klein; JCP Mello
• Keywords: Sterculiaceae

Guazuma ulmifolia Lam. (Sterculiaceae), popularly known as „Mutamba“, is a tropical-American plant found from Mexico to southern South America. In the popular medicine of several Latin-American countries, it used for treatment burns, diarrhea, inflammations and alopecia. Polysaccharides, epicatechin (EP) procyanidin oligomers, such procyanidins B2 (PB2) B5, three trimers [procyanidin C1; epicatechin-(4β→6)-epicatechin-(4β→8)-epicatechin; epicatechin-(4β→8)-epicatechin-(4β→6)-epicatechin] one tetramer have been isolated identified its extract [1]. The anti-diabetic properties [2], hypotensive vasorelaxant activity [3], anti-ulcer [4], anti-bacterial activities [5], antiviral [6] bark, aerial parts, fruits, crude fractions were attributed presence proanthocyanidins. preliminary stability dried extracts bark G. containing or not colloidal silicon dioxide (CSD) was evaluated. physical-chemical compatibility CSD in evaluated 21 days storage under stress conditions temperature (45±2°C) humidity (75±5%). Thermal analysis (TG) supplemented using selective high-performance liquid chromatography (HPLC) determination characteristic constituents (chemical markers), namely PB2 EP. results showed that an appropriate compound use chemical marker control quality ulmifolia. study there no significant difference between two extracts. On other hand, considering TG data high temperatures involved, suggest would increase