An Easy Stereoselective Copper(I)-Catalyzed Synthesis of (E)-3-Trifluoromethylbut-2-en-3-ynoate via Palladium-Free Stille Coupling Reaction

• DOI: 10.1055/s-0031-1290596
• Publication Date: 2012-02-28T19:16:37Z
• Authors: Mohamed Abarbri; Khalid Zine; Julien Petrignet; Jérôme Thibonnet
• Keywords: (E)-2,3-DIFLUORO-3-STANNYLACRYLIC ESTER; DERIVATIVES; [SDV]Life Sciences [q-bio]; copper-catalyst; ALKENYLTRIMETHYLSTANNANE FUNCTIONS; BETA; CONVENIENT PREPARATION; ACIDS; beta-unsaturated ester; 01 natural sciences; palladium-free; trifluoromethylbut-2-en-3-ynoate; 0104 chemical sciences; FUNCTIONALIZED CONJUGATED DIENE; ARYL IODIDES; BENZANNULATION REACTION; beta-tributylstannyl-alpha; STEREODEFINED ENYNES

AbstractIn most cases, clean formation of (E)‐configurated products is observed.