ShearWave™ Elastography BE1 Multinational Breast Study: Additional SWE™ Features Support Potential to Downgrade BI-RADS®-3 Lesions

• DOI: 10.1055/s-0033-1335523
• Publication Date: 2013-05-24T18:30:39Z
• Authors: F. Schäfer; R. Hooley; R. Ohlinger; U. Hahne; H. Madjar; W. Svensson; C. Balu-Maestro; V. Juhan; A. Athanasiou; A. Mundinger; B. Order; M. Locatelli; D. Cosgrove; O. Wolf; J. Henry; M. Moutfi; J. Gay; C. Cohen-Bacrie
• Keywords: Downgrade; BI-RADS

<b>Purpose:</b> To determine the benefit of ShearWave™ Elastography (SWE™) in ultrasound characterization BI-RADS^® 3 breast lesions a diagnostic population. <b>Materials and Methods:</b> 303 (mean size: 13.2 mm, SD: 7.5 mm) from multicenter BE1 prospective study population were analyzed: 201 (66 %) had cytology or core biopsy, remaining 102 minimum follow-up one year; 8 (2.6 malignant. 7 SWE features evaluated with regard to their ability downgrade benign masses. The performance each feature was assessed by evaluating number correctly reclassified impact on cancer rates within new 3‘ lesion group. <b>Results:</b> No malignancies found an E-color “black dark blue”, which allowed downgrading 110/303 masses (p < 0.0001), non-significant increase malignancy rate 2.6 % 4.1 %. E-max ≤ 20kPa m/s) able 48/303 0.0001) lower (3.1 %). other useful for reclassifying lesions. <b>Conclusion:</b> Applying simple reclassification rules, assessment maximum stiffness sub-group This accompanied class.