Evaluation of Improvement in Exercise Capacity after Pulmonary Endarterectomy in Patients with Chronic Thromboembolic Pulmonary Hypertension: Correlation with Echocardiographic Parameters

• DOI: 10.1055/s-0033-1336012
• Publication Date: 2013-04-05T18:54:37Z
• Authors: Murat Sunbul; Tarik Kivrak; Elif Eroglu; Beste Ozben; Bedrettin Yildizeli; Bulent Mutlu; Alper Kepez
• Keywords: Concomitant

The study evaluates the alterations in exercise capacity of chronic thromboembolic pulmonary hypertension (CTEPH) patients after endarterectomy (PEA) and investigates echocardiographic parameters associated with degree functional recovery.Thirty consecutive diagnosis CTEPH (17 males; mean age, 45.9 ± 15.1 years) who had been referred for PEA operation were included study. Each patient underwent transthoracic echocardiography 6-minute walk test (6-MWT) before 6 months PEA.After PEA, 6-MWT distances significantly increased (242.8 112.8 m vs. 423.6 89.1 m, p < 0.001), whereas systolic artery pressures right ventricular dimensions decreased (86 25.1 mm Hg 41.9 15.6 Hg, 0.001 42.1 10.1 35.3 5.6 mm, 0.001, respectively). Magnitude change distance (Δ-6-MWT) was found to be correlated concomitant tricuspid annular plane excursion left myocardial performance index (r: 0.518, p: 0.004 r: -0.385, 0.043, Linear regression analysis revealed preoperative as an independent negative predictor delta-6-MWT (beta: -0.89, t: -3.97, 0.001).CTEPH more severely depressed at baseline displayed relatively greater recovery our Improvement improvement reflecting functions rather than pressure operation.