First Neonatal Demise with Travel-Associated Zika Virus Infection in the United States of America

• DOI: 10.1055/s-0037-1601890
• Publication Date: 2017-04-13T23:08:27Z
• Authors: Nikolaos Zacharias; Janice Whitty; Sarah Noblin; Sophia Tsakiri; Jose Garcia; Michael Covinsky; Meenakshi Bhattac...; David Saulino; Nina Tatevian; Sean Blackwell
• Keywords: Zika Virus; Microcephaly; Ventriculomegaly; Single umbilical artery

Zika virus is increasingly recognized as a fetal pathogen worldwide. We describe the first case of neonatal demise with travel-associated infection in United States America, including novel prenatal ultrasound finding. A young Latina presented to our health care system Southeast Texas for at 23 weeks gestation. Fetal Dandy-Walker malformation, asymmetric cerebral ventriculomegaly, single umbilical artery, hypoechoic knee, dorsal foot edema, and mild polyhydramnios were noted upon initial screening sonography 26 weeks. growth-restricted, microcephalic, arthrogrypotic infant was delivered alive 36 but died within an hour despite resuscitation. The karyotype normal. Flavivirus IgM antibodies identified serum puerpera, once she disclosed that had traveled from El Salvador early second trimester. cord brain. arthritis may precede congenital arthrogryposis cases be detectable by sonography. Physician vigilance required optimally address significant enduring global threat.