Palladium-Catalyzed Asymmetric Heck–Matsuda Reaction of 1,4-Dihydroquinolines with Aryl Diazonium Salts

• DOI: 10.1055/s-0037-1610712
• Publication Date: 2019-05-14T18:56:13Z
• Authors: Ze-Zhen Jiang; Yang-Jie Jiang; Juan Du; Di Chen; Chang-Hua Ding; Bin Xu; Xue-Long Hou
• Keywords: Heck Reaction

A palladium-catalyzed asymmetric Heck–Matsuda reaction of N-Boc-1,4-dihydroquinolines and aryl diazonium tetrafluoroborates is realized in moderate to high yields with enantioselectivities. The method provides an efficient route access optically active 2-arylhydroquinolines.